Speakers

Keynote Speaker 2023


Prof. Hongping Zhang

Chengdu University

Biography:

Hong Ping Zhang received his BS and PhD degrees from Southwest Jiaotong University (SWJTU). He conducted postdoctoral research at State Key Laboratory of Environmentally Friendly Energy Materials, Southwest University of Science and Technology and worked as an Associate Professor in the university in 2020–2022. He joined Institute for Advanced Study, and School of Mechanical Engineering at the Chengdu University (CDU) as a Professor in 2022. He has published more than 100 papers. His work has been cited over 3900 times, with an h-index of 31. He is a researcher in material science and engineering with research interests focusing on structure-process-property relation of (a) density functional theory calculation or molecular modeling for materials surface and interface interactions (b) nanomaterials reinforced composites and structures, particular for structural applications and (c) biomaterials, especially the novel osteoporostic bone repair materials or wound dressing.

Speech Title: Novel sponge like hydrogel for Diabetic Wound Regeneration

Abstract:

Diabetes has emerged as one of the major diseases that threatens public health and poses huge clinical challenges and financial burdens annually.[1, 2] This is a chronic complication that is characterized by extremely delayed wound healing that leads to bacterial infections.[3] An important factor that is responsible for this complication is the reduced antioxidant production in such patients. Thus, novel wound dressing are needed to be developed to meet the requirements. Here, I would like to introduce one novel hydrogel for diabetic wound regeneration. On the one side, hydrogels with soft and wet properties have been intensively investigated for chronic disease tissue repair. Nevertheless, tissue engineering hydrogels containing high water content are often simultaneously suffered from low porous size and low water-resistant capacities, leading to undesirable surgery outcomes. Here, a novel sponge-like macro-porous hydrogel (SM-hydrogel) with stable macro-porous structures and anti-swelling performances was developed via a facile, fast yet robust approach induced by Ti3C2 MXene additives. The MXene-induced SM-hydrogels (80% water content) with 200-300 μm open macropores, demonstrating ideal mass/nutrient infiltration capability at approximately a 20-fold higher water/blood-transport velocity over that of the nonporous hydrogels. Moreover, the highly strong interactions between MXene and polymer chains endow the SM-hydrogels with excellent anti-swelling capability, promising equilibrium SM-hydrogels with identical macro-porous structures and toughened mechanical performances. The SM-hydrogel with versatile functions such as facilitating mass transport, antibacterial (bacterial viability in SMPAAM below 25%) and reactive oxygen species (ROS) scavenging capacities (96% scavenging ratio at 120 min) synergistically promotes diabetic wound healing (compared with non-porous hydrogels the wound closure rate increased from 39% to 81% within 7 days).Therefore, the durable SM-hydrogels exhibited connective macro-porous structures and bears versatile functions induced by MXene, demonstrating its great potential for wound tissue engineering.


To be updated...


CoMSE Past Speakers

                           

Dr. Matthias Bönisch                        Ph.D Pao Ter Teo

Department of Materials    Faculty of Bioengineering and Technology

Engineering Belgium              Universiti Malaysia Kelantan (UMK)

        Belgium                                               Malaysia

比利时材料工程系       马来西亚吉兰丹大学(UMK)生物工程与技术学院